I recently came across a remarkable case report in The American Journal of Medicine concerning a bodybuilder with hypervitaminosis D complicated by hypercalcemia and acute kidney injury, for which the intoxication was attributed to use of a vitamin D-containing dietary protein supplement. (Van et al. 2018) Finding the authors’ discussion intriguing, I offered some thoughts on the matter as a Letter to the Editor. As the Journal declined to publish my commentary, I offer it openly here.